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Th HSV-1(hrR3) (22) and measuring -galactosidase activity at 5 h postinfection. The neutralization titer represents the dilution of antiserum needed to reduce -galactosidase activity to 50 of the maximum seen with no serum added. b Virus infection was measured by plaque formation by HSV-1(KOS) on Vero cells, using the black plaque assay. The neutralization titer represents the dilution of antiser

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