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Holesterol in R (48 ?42) compared to Z (27 ?42) mg/dl, p = 0.07. The final total cholesterol was similar between groups. No between group changes in HDL or triglycerides were seen. See Table 1 for changes in vessel wall parameters in the 2 groups. Plaque volume regressed in R while it progressed in Z and total vessel volume followed the same trend (p = 0.11). No between group differences in lumen
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Plemental Fig. S2). In contrast, I54A 32 was degraded slightly faster than wild type at 37 and even faster at 42 (Fig. 1 and supplemental Fig. S2).JOURNAL OF BIOLOGICAL CHEMISTRYChaperone Binding toFIGURE 1. In vitro degradation of 32 by ClpYQ and FtsH proteases. 32 (2.4 g) was incubated with ClpQ (1.0 g) and ClpY (2.5 g), or 32 (1.0 g) was incubated with FtsH (2.0 g), in a reaction mixture (6
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