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The three BCAAs, leucine, isoleucine, and valine, make up approximately one third of all amino acids in muscle tissue.
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Gnificantly down-regulated (P = 0.09) in BRAF-mutant cancers compared to KRAS-mutant cancers (Fig. 2). Furthermore, these three miRNAs were shown to be significantly dysregulated in BRAF-mutant cancers compared to normal colonic mucosa (n = 11; Fig. 2), which suggests that the alteration in these miRNA expressions may contribute, at least in part, to the carcinogenesis of BRAF-mutant tumors. Of th
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