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Ompared to WT mice [12,15], suggesting that, at least with respect to K. pneumoniae, direct effects of SPA on host defense function (i.e. enhancement of phagocytosis) are more important than the pleiotropic indirect effects on the BAL proteome.8. 9.10.Additional materialAdditional file 1 MIAPE: Gel Electrophoresis. File containing Minimum information about a proteomics experiment - Gel Electrophor
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Tion.Conclusion In summary, this proteomic comparison of BAL proteins in WT and SP-A-/- mice under normal conditions and after infection with K. pneumoniae provide us with the following information. 1) Proteins involved in the regulation of host defense and redox balance are reduced in the SP-A-/- mice under baseline conditions. Prior evidence that the alveolar macrophages of SP-A-/- mice are dysf
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