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Gnificantly down-regulated (P = 0.09) in BRAF-mutant cancers compared to KRAS-mutant cancers (Fig. 2). Furthermore, these three miRNAs were shown to be significantly dysregulated in BRAF-mutant cancers compared to normal colonic mucosa (n = 11; Fig. 2), which suggests that the alteration in these miRNA expressions may contribute, at least in part, to the carcinogenesis of BRAF-mutant tumors. Of th
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Rias Y, De Baetselier P, Van Ginderachter JA. Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions. Int J Dev Biol. 2011;55(7-9):861-867. doi:10.1387/ijdb.113371dl. PubMed 45. Allavena P, Sica A, Garlanda C, Mantovani A. The Yin-Yang of tumorassociated macrophages in neoplastic progression and immune surveillance. Immunol Rev. 2008;222:155-161. doi:10.1111/j.1600-065
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