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The remaining 16 (36 ) patients. All major clinical characteristics resulted comparable among the two groups of patients (EGFR GCN 2.12 and < 2.12). In particular no differences were noticed for sex, age at diagnosis and previous lines of chemotherapy (Table 1). On the contrary in patients showing a CISH EGFR GCN 2.12 we observed 10 partial remissions (36 ) whereas 1 partial remission (6 ) was o
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Tic cancer, there is considerable heterogeneity in the molecular make-up, MAPK/ERK pathway activation states, and clinical outcome in this disease. We analyzed the expression levels of CNKSR1, a scaffold that influences MAPK/ ERK pathway activity, in clinical pancreas cancer specimens and their impact on survival of patients with pancreatic cancer. Methods: Immunohistochemical staining for CNKSR1
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Tic cancer, there is considerable heterogeneity in the molecular make-up, MAPK/ERK pathway activation states, and clinical outcome in this disease. We analyzed the expression levels of CNKSR1, a scaffold that influences MAPK/ ERK pathway activity, in clinical pancreas cancer specimens and their impact on survival of patients with pancreatic cancer. Methods: Immunohistochemical staining for CNKSR1
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